Laboratory Website Revision 17

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8
SAMPLE REQUESTS AND HANDLING

8.1 Details required for all specimens except blood transfusion specimens

(NB: See section 8.9 for Blood Transfusion requirements)

 

8.1.1 On the specimen container:

                   Full name of patient

                   Date of birth / Hospital (medical record) number

                   Site of origin, if other than blood

                   Date sample taken (desirable)

                   Signature or initials of person taking the sample on pre-printed labels (desirable)

 

8.2 Essential Information on the Request Card (or electronic equivalent)

There is a separate request form for Microbiology and histology and a combined Biochemistry/Haematology/Immunology form. The information needed on the request to ensure appropriate examination and result interpretation is:

 

    • Full name of patient (corresponding to that on the specimen container)

     Date of birth/ Hospital (medical record) number (corresponding to that on the specimen container)

    • Name of consultant of care and location

    • Relevant clinical details

    • Specimen Type/Nature of specimen (and site if relevant)

    • Nature of examinations/tests required

 

        NB:  Specimens will not be accepted without a minimum of two forms of identification on both the specimen container and on the form. 

 

8.3 Desirable Information on the Request Card

        ·        Clinical Information.  History of travel may also be pertinent. 

        ·         Any anticoagulant or antibiotic therapy

        ·         Risk of infection

        ·         Date and Time Sample collected (which is sometimes essential, e.g., GTT and Cortisol)

        ·         Patient’s address

        ·         Patient’s sex

        ·         Signature of requesting clinician

        ·         Clinician’s contact number

        ·         Designate urgent, routine or “ASAP” as required

 

        Notes: An adequately completed request form once accepted in the laboratory initiates an agreement for services.

        The laboratory will cooperate with users or their representatives if clarification of a request is required.

 

        Separate request forms should be sent for different testing timelines, e.g., 24hr urine requests that require separate collections.

        Users are asked for feedback on request forms through user meetings and surveys.

 

8.4 Patient Preparation and Consent

Where a patient presents in outpatients with a pathology request form, consent for phlebotomy is assumed.  Where suitable, phlebotomy staff ask inpatients for permission to proceed. For certain referral tests (such as genetic screening), required consent will be obtained by filling out the relevant test request form signed by the patient. Patients should be aware that where tests are referred important clinical information and family history will be disclosed to relevant healthcare professionals and sample material may be stored for a period of time. Procedures for patient preparation are available through the phlebotomy department.

Genetic request forms are required for all genetic tests/screens. These are available on Q Pulse and include:

LF-HAEM-0055 Genetic Analysis Request Form Crumlin

EXT-GEN-0086 Eurofins/Biomnis Request/Consent Form for Genetic Testing and Generic Genetic Testing Consent Form

 

8.5 Specimen Reception and Rejection Process

Laboratory staff inspect incoming specimens to ensure that the request form and the labelling of the specimen container are completed as outlined and that the quality of the specimen is adequate. This is to secure correct patient identification and avoid inaccurate results.  The laboratory will inform the user of any problems with regard to specimens as soon as possible after receipt, for example, rejection due to

  • insufficient sample
  • haemolysis or lipaemia 
  • incorrect labelling
  • inappropriate container used
  • specimen transported or held in an inappropriate environment
  • leaking specimen containers
  • clotting in anticoagulated samples

 

These events will be recorded as rejections on the laboratory information system and may be raised as non-conformities. Any trends will be reported to the service user.

 

8.6 Additional Examinations

Additional examinations required on samples already sent to the laboratory should be sent on a correctly labelled request form sheet.  Add on tests must be clearly indicated on the bottom of the form and listed. The request can be sent in the pneumatic chute or faxed to the fax located in the laboratory (01) 2064507.   Requests for further work on histology specimens should be faxed to 01-2064619.  Verbal requests for urgent examinations to samples received must be followed with written confirmation by a request form sheet or electronic equivalent as soon as possible or at least same day.

 

8.7 Key Factors that may affect test performance or interpretation of results:

The following key factors are essential to ensure correct test performance or interpretation of results when taking samples and filling in request forms:

 

  • ·         Patient details must be correct on the request form
  • ·         Relevant clinical details must be on the request form
  • ·         Correct identification of the patient
  • ·         Some examinations require patient preparation (e.g., Fasting)
  • ·         Samples must be taken in the appropriate manner, order of draw and correct volumes
  • ·         Details and time of phlebotomy must be correct on the request form
  • ·         Samples must be placed in appropriate containers/blood tubes
  • ·         Samples must be appropriately labelled (see above 8.1 and 8.9 for Blood Transfusion)
  • ·         Samples must not be poured from one blood tube into another (e.g., anticoagulant cross contamination)
  • ·         Coagulation samples must not be contaminated with heparin from extraneous sources such as flushing a line
  • ·         Samples must not be taken from an arm with a running I.V.
  • ·         Clotted samples or samples containing fibrin strands will affect results
  • ·         High lipid levels in the plasma of samples will adversely affect Haematological investigations and some Biochemistry analytes
  • ·         Samples will be adversely affected by delay in receipt to the laboratory
  • ·         Samples will be adversely affected by heat / cold degradation

 

Other factors, including relevant patient preparation (e.g., fasting), special specimen handling or interfering substances relating to individual tests may be listed in the specimen requirements appendices.

If patients require information/instructions for patient-collected samples, this should be obtained from OPD Phlebotomy.

 

8.8 Safe disposal of materials used in sample collection

All sharp material used in the collection of blood samples must be disposed of in a sharps bin only.  All soiled soft waste, e.g., blood stained gauze must be disposed of in a suitable biohazard bin (located on all the phlebotomy trolleys in-house). Any clean waste, e.g., packaging from equipment is placed in a clear bag for domestic waste.  All staff must adhere to MP-GEN-0007 Staff health and Safety Manual and PP/C/IC-5 Policy for Clinical Waste

 

8.9 Blood Transfusion Requests:

        8.9.1 Completing the Request Form

All test requests are made by registered Medical Doctors. The request form may be completed by a nurse, based on either a prescription or protocol.

A full Blood group and antibody screen (for irregular red cell antibodies) is performed on all samples requesting a Group and screen and / or Crossmatch. The sample is held for crossmatching for 72 hrs from venepuncture.

 

8.9.2 Two Sample Requirement

Group Specific Blood Products will only be issued when the Laboratory has confirmed the patient blood group on a second independently taken sample. Patients who have no previous group on record in Blackrock and are likely to need products, or are scheduled to go to theatre should have a second sample taken. Group and Screen reports on first time samples will indicate that another sample will be required. In an emergency situation Group O red cells may be issued without a confirmatory patient group. Samples used for first groups include any Blackrock Clinic inpatients or outpatients tested since 2000.

 

8.9.3 Electronic Issue / Serological Crossmatch

The majority of patients grouped twice will qualify for Electronic Issue (EI) of Red Cells. These patients are issued group specific red cells without actual serological testing which only takes a few minutes. Some patients don’t qualify for EI (including those with antibodies, some clinical conditions, those with anomalous groups). These need to be serologically crossmatched which takes approximately 40 mins once the required RCs are in stock.

 

8.9.4 Ordering Products

A registered Medical Doctor must prescribe all blood components and products for transfusion. Platelets must be ordered by a Consultant or Registrar (exception – emergencies or after discussion with the Consultant). Staff permitted to place the request with the laboratory after viewing the written prescription are defined in PP/C/HW-59: Ordering of Blood components and Blood products on hospital Q pulse (Resident Medical Officer (RMO), Registrar, Consultant, Perfusionist or Nurse).

 

8.9.5 Correct Specimen Type

The correct specimen type for blood transfusion is a plastic 6ml, pink-topped K2EDTA sample. The sample must not be grossly haemolysed.

The sample must be fully labelled as per section 8.9.7.1 of this manual. Pre-printed labels may not be used.  Samples with missing or incorrect details will be rejected.  The request form (LF-BT-0039) must be completed as per section 8.9.7.1 of this manual. Samples will not be processed if the relevant information is not completed on the request card.

All inpatient samples (i.e., those which may be used for crossmatching) must be labelled immediately from the patient wristband. Samples taken from outpatients or external patients are not used for crossmatching / product issue.

Specimen types for other test requests are listed in the appendices. Section 19.4 for Blood Transfusion.

 

8.9.6 Valid Sample Age

Samples used for crossmatching must be less than 72 hrs old at time of transfusion. A fresh sample must be taken for Group, Screen and Crossmatch if more than 72 hrs have elapsed (or will have elapsed by the time of infusion) since the patient was previously bled, regardless of previous transfusions/pregnancies.

 

8.9.7 Blood Transfusion Specimen and Request Form Labelling

        8.9.7.1 On the specimen

Sample labels must be handwritten, pre-printed addressograph labels are not acceptable. Crossmatch / Group and Screen samples must be labelled immediately after taking, from the patient wristband.

 

All of the following essential information is required:

• Full name of patient, correctly spelt as it appears on their wristband

(e.g., Joe P Bloggs)

• Hospital number

• Date of birth

• Date & time of venepuncture

• The initials or signature of the person taking the sample

Samples which are inadequately or incorrectly labelled will be rejected and a repeat requested.

Alterations to essential sample information will not be accepted for transfusion purposes.

 

        8.9.7.2 On The Request Card

All of the following essential information is required:

• Full name of patient (exactly as on sample)

• Hospital Number and Date of Birth (exactly as on sample)

• Gender

• Name of Consultant

• Name of Ward/Department

• Signature, date and time of specimen collection

• Test and/or product required with date and time

• Specific requirements, e.g., CMV negative, irradiated products.

 

The following important information to be given where available:

• Reason for transfusion or relevant clinical details

• “Important Transfusion History” section complete

 

If the “Essential Information” section has not been completed, only the Venepuncturist can amend it. Significant Patient Demographics cannot be amended on Request forms – a new sample will be required. 

Laboratory staff can add or cancel test requests and Transfusion History on the request form when informed by Clinical Staff. 

 

8.9.8 Patient Information Leaflet (Information on Blood Transfusion):

With the exception of emergency transfusions, all patients that are Group and Screened/Crossmatched in Blackrock Clinic receive a copy of the Patient Information Leaflet. This leaflet contains information regarding the reason for the transfusion, risks, alternatives and possible reactions to transfusions.  The declaration form is signed by the patient and stapled to either the consent form or the blood prescription form in the patient’s chart.

Before blood or blood products are administered the doctor or the nurse hanging the blood must ensure that verbal consent is obtained from the patient and the appropriate box is ticked on the prescription form. (Exception - emergencies)

Ref: PP/C/HW-54 Hospital Q pulse